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Archivos Venezolanos de Farmacología y Terapéutica

versión impresa ISSN 0798-0264

Resumen

PRIETO, Delia; ANEZ, Roberto; ROJAS, Joselyn  y  BERMUDEZ, Valmore. Effect of Hibiscus sabdariffa L aqueous infusion administration on body mass index, appetite and satiety in individuals with grade I obesity. AVFT [online]. 2013, vol.32, n.3, pp.34-40. ISSN 0798-0264.

Introduction: Several studies have demonstrated Hibiscus sabdariffa L administration effects on weight reduction in experimental models. The aim of this study was to evaluate the administration of an aqueous infusion prepared from calyxes Hibiscus sabdariffa L on body mass index, appetite and satiety in type I obese individuals. Materials and Methods: 30 adults with obesity type 1 were randomly assigned to receive an infusion of Hibiscus sabdariffa L or placebo during 3 weeks twice daily. Ponderal evaluation was performed using BMI and the effect of administration of treatment/placebo on appetite and satiety sensation was assessed by visual analog scale (VAS). Qualitative variables were expressed as absolute and relative frequencies and continuous variables as mean ± SD. Student´s t test was performed for differences between means and intragroup comparisons according time (week 1, 2 and 3) was assessed by repeated measures ANOVA´s test (GLM). Results: The individuals treated with Hibiscus sabdariffa L infusion exhibited a significant BMI reduction when compared with those receiving placebo. No significant differences were found in appetite and satiety between placebo and Hibiscus-treated group in any week studied. Conclusions: We demonstrated a short-term reduction in BMI by Hibiscus sabdariffa aqueous infusion administration in type I obesity individuals not related to appetite or satiety changes. A possible thermogenic effect could explain this weight reduction.

Palabras clave : Hibiscus sabdariffa; obesity; body mass index; satiety; appetite.

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