Resumen

MORALES, Adaucio Ramón  y  MONTILVA, Lourdes Mariela. Anthropometric parameters: predictive capacity and utility as diagnostic tests of insulin resistance in adolescents. Rev. Venez. Endocrinol. Metab. [online]. 2017, vol.15, n.3, pp.195-205. ISSN 1690-3110.

Objective: To determine the capacity of the body mass index (BMI), waist to height ratio (WHtR) and abdominal circumference (AC) to predict insulin resistance (IR) according to the measurement site of the AC, and determine the effectiveness of such indicators to distinguish between healthy subjects and subjects with IR. Methods: In 31 institutions of secondary and university education at the Iribarren Municipality, Lara State, Venezuela, 798 adolescents of both sexes (404 men) between 15 and 19 years of age were enrolled. Adolescents signed informed consent. Socioeconomic stratum, weight, height and AC were evaluated in three anatomical sites: above the iliac crests, midpoint and below the costal margin. We calculated BMI and WHtR for each site. Basal insulin was determined and Homeostasis Model Assessment Insulin Resistance (HOMA-IR) was calculated. Non-parametric tests, logistic regression and receiver operating characteristic (ROC) curves were performed. Results: It was demonstrated that IR is a function of WHtR, AC and BMI, being this association stronger with WHtR. The predictive capacity of WHtR was better in the upper and middle segments of the abdomen. As diagnostic tests, all had equal efficacy to distinguish between healthy subjects and subjects with IR, however, in adolescents allow to classify a greater number of healthy subjects. Conclusion: All anthropometric parameters are effective, but in adolescents, they identify a greater number of healthy subjects. It is proposed to unify AC measurement site, immediately below the costal ridge or midpoint of the abdomen, because they are the sites most likely to predict IR.

Palabras clave : Anthropometric parameters; diagnostic test; prediction; insulin resistance; adolescent.

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