Abstract

VEINTIMILLA-MORALES, Nathaly Gabriela; ASPIAZU-HINOSTROZA, Karla  and  PRIETO-FUENMAYOR, Carem Francelys. Congenital factors of arterial thrombotic disorders in newborns. Salud y Vida [online]. 2022, vol.6, n.12, pp.4-36.  Epub Jan 17, 2023. ISSN 2610-8038.  https://doi.org/10.35381/s.v.v6i12.1957.

Neonatal arterial thrombosis represents 5.8% of all known types of thrombosis in newborns, this makes this disease a specific point of focus for its timely diagnosis, and to decipher the congenital factors of greater recurrence, a systematic review PRISMA was performed, where 20 articles of cross-sectional observational type were evaluated, detailing the results obtained in terms of the most recurrent congenital factor which in this case is male sex, prematurity and genetic defects have also been mentioned biochemical and molecular markers mostly evaluated in this sample, showing that in these cases the biochemical markers frequently analyzed are: Antithrombin III, Protein C and S, antiphospholipid antibodies and homocysteine and as molecular markers are evaluated with greater recurrence to: Factor V Leiden and the prothrombin gene G20210A.

Keywords : Neonatal arterial thrombosis; MTHFR mutation; leiden factor V mutation; G20210 mutation.

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