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Archivos Venezolanos de Farmacología y Terapéutica

Print version ISSN 0798-0264

Abstract

MEDEROS CUERVO, Lilian María et al. Meningitis and tuberculosis dissemination in acquired immunodeficiency syndrome (AIDS) patients. AVFT [online]. 2010, vol.29, n.2, pp.35-38. ISSN 0798-0264.

Meningoencephalitis due to opportunistic germs has an important place among the neurological diseases in AIDS patient. Treponema pallidum and Mycobacterium tuberculosis (bacteria), Cryptococcus neoformans (fungi), Toxoplasma gondii (protozoa), and Papovirus JC (virus) are the most frequently germs found in each group. Likewise, in immunodepressed patients in general and in HIV/AIDS patients in particular, mixed infections have been frequently found, basically as a consequence of the patient’s deteriorated immunological barrier. Tuberculosis meningitis (TBM) is the most severe form of presentation of the extrapulmonary tuberculosis. Its unspecific symptoms, the delay in the etiological diagnosis, and the severe neurological sequelae that can appear in this specific type of patient make of this disease an important health problem, in both developed and developing countries. This study describes the "first case" of meningitis and disseminated infection by Mycobacterium tuberculosis in a Cuban patient infected by the human immunodeficiency virus.

Keywords : meningitis; meningoencephalitis; Mycobacterium tuberculosis; acquired immunodeficiency syndrome (AIDS); human immunodeficiency virus (HIV).

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