Abstract

BURGESSER, María Virginia; CAMPS, Diego; DILLER, Ana  and  CAEIRO, Gastón. Anemia hemolítica autoinmune como manifestación inicial de linfoma hodgkin. Rev. venez. oncol. [online]. 2011, vol.23, n.1, pp.34-37. ISSN 0798-0582.

In this work we report and study a case of 66 year old woman, whit diagnosis of hemolytic anemia, which was refractory to treatment and she required splenectomy. The patient presented inguinal lymphadenopathy which biopsy has determined a partial infiltration of B-cells CD20 + and CD30 + with atypia and high growth factor. The bone marrow biopsy informed an increased number of T lymphocytes. Four month later, the patient complained due to the appearance of inguinal and axillaries lymph nodes, which biopsy revealed a nodular sclerosis Hodgkin lymphoma. The bone marrow biopsy showed infiltration by lymphoproliferative disease. Although the association between hemolytic anemia and Hodgkin lymphoma is less frequent, this fact should be taken into account in searching its cause and reaching the diagnosis of a probable underlying lymphoproliferative process.

Keywords : Cancer; lymphoma; Hodgkin; hemolytic; anemia; adenopathy.