<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0016-3503</journal-id>
<journal-title><![CDATA[Gen]]></journal-title>
<abbrev-journal-title><![CDATA[Gen]]></abbrev-journal-title>
<issn>0016-3503</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Venezolana de Gastroentereología]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0016-35032025000100047</article-id>
<article-id pub-id-type="doi">10.61155/gen.v79i1.732</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Litiasis biliar primaria recurrente]]></article-title>
<article-title xml:lang="en"><![CDATA[Recurrent primary biliary lithiasis]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Carrión]]></surname>
<given-names><![CDATA[Lorena]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sivira]]></surname>
<given-names><![CDATA[Pedro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Folkmanas]]></surname>
<given-names><![CDATA[William]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Naddaf]]></surname>
<given-names><![CDATA[Rubén]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Central de Venezuela  ]]></institution>
<addr-line><![CDATA[Caracas ]]></addr-line>
<country>Venezuela</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Caracas  ]]></institution>
<addr-line><![CDATA[Caracas ]]></addr-line>
<country>Venezuela</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Caracas  ]]></institution>
<addr-line><![CDATA[Caracas ]]></addr-line>
<country>Venezuela</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Caracas  ]]></institution>
<addr-line><![CDATA[Caracas ]]></addr-line>
<country>Venezuela</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2025</year>
</pub-date>
<volume>79</volume>
<numero>1</numero>
<fpage>47</fpage>
<lpage>50</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://ve.scielo.org/scielo.php?script=sci_arttext&amp;pid=S0016-35032025000100047&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://ve.scielo.org/scielo.php?script=sci_abstract&amp;pid=S0016-35032025000100047&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://ve.scielo.org/scielo.php?script=sci_pdf&amp;pid=S0016-35032025000100047&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen La litiasis coledociana o litiasis de la vía biliar principal se define como la presencia de cálculos en el colédoco, como resultado de su migración desde la vesícula (litiasis coledociana secundaria) o de su formación in situ en la vía biliar (litiasis coledociana primaria). El objetivo del trabajo es presentar un caso de ictericia obstructiva biliar primaria recurrente de paciente colecistectomizada hace 3 años. Se trata de paciente femenino de 62 años, con antecedente de Colangiopancreatografía retrógrada endoscópica (CPRE) extra institucional por coledocolitiasis y colecistectomía convencional en 2021 y CPRE en 2023 en nuestra institución, quien refiere inicio de enfermedad actual el día 06/06/2024 caracterizado por presentar dolor abdominal de aparición insidiosa, localizado en epigastrio, que se irradia a hipocondrio derecho e izquierdo, de tipo cólico, de moderada intensidad, concomitante nauseas, 24 horas después se asocia ictericia generalizada y fiebre de 38.5°C que cede a la administración de dipirona IV, por lo que acude a nuestro centro donde es evaluada, se realiza ultrasonido abdominal, evidenciando colédoco dilatado en su porción media y distal (10 mm), exámenes de laboratorio que reportan leucocitos en 23.300, neutrófilos 93.1%, AST: 142 U/L, ALT:132 U/L, ALP: 422 U/L, BT: 10.20 mg/dl, BD: 9.42 mg/dl. Se realiza CPRE con evolución clínica y bioquímica favorable por lo que se egresa. En el caso reportado, es importante el antecedente de colecistectomía; en general, la presencia de cálculos dentro del conducto biliar después de la colecistectomía generalmente se considera "retenida" dentro de los 2 años posteriores a la colecistectomía o "recurrente" después de este período.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Common bile duct lithiasis, or lithiasis of the main bile duct, is defined as the presence of stones in the common bile duct, either due to their migration from the gallbladder (secondary common bile duct lithiasis) or their formation in situ within the bile duct (primary common bile duct lithiasis). The aim of this study is to present a case of recurrent primary biliary obstructive jaundice in a patient who underwent cholecystectomy three years ago. The patient is a 62-year-old woman with a history of extra-institutional endoscopic retrograde cholangiopancreatography (ERCP) for choledocholithiasis and conventional cholecystectomy in 2021. She also underwent ERCP in 2023 at our institution. The patient reported the onset of her current condition on June 6, 2024, characterized by abdominal pain of insidious onset, located in the epigastrium and radiating to the right and left hypochondrium. The pain was colicky, of moderate intensity, and associated with concomitant nausea. Twenty-four hours later, the patient developed generalized jaundice and a fever of 38.5°C, which subsided after the administration of intravenous dipyrone. She then presented at our center, where an evaluation was conducted. An abdominal ultrasound revealed a dilated common bile duct in its middle and distal portions (10 mm). Laboratory tests showed leukocytosis (23,300 white blood cells), 93.1% neutrophils, AST: 142 U/L, ALT: 132 U/L, ALP: 422 U/L, total bilirubin: 10.20 mg/dL, and direct bilirubin: 9.42 mg/dL. ERCP was performed, resulting in favorable clinical and biochemical outcomes, and the patient was discharged. In this case, the history of cholecystectomy is particularly relevant. Generally, the presence of stones within the bile duct after cholecystectomy is classified as "retained" if detected within two years of the surgery or "recurrent" if identified after this period.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[litiasis coledociana]]></kwd>
<kwd lng="es"><![CDATA[litiasis coledociana primaria]]></kwd>
<kwd lng="es"><![CDATA[litiasis coledociana secundaria]]></kwd>
<kwd lng="es"><![CDATA[colecistectomía]]></kwd>
<kwd lng="en"><![CDATA[common bile duct stones]]></kwd>
<kwd lng="en"><![CDATA[primary common bile duct stones]]></kwd>
<kwd lng="en"><![CDATA[secondary common bile duct stones]]></kwd>
<kwd lng="en"><![CDATA[cholecystectomy]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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