Abstract

ALVES UCHOA, Ruthinéia Diógenes et al. Immunohistochemical expression of macrophagic cellular population  in periodontal disease.. Acta odontol. venez [online]. 2006, vol.44, n.1, pp.7-13. ISSN 0001-6365.

The important function of immunological reaction in periodontal disease has been studied by several reports. In order to achieve contributive information to the knowledge of the pathogeny of this disease, an immunohistochemical analysis of the density and distribution of macrophagic cells was realized using anti-CD68 antibody  in 17 cases of chronic gingivitis and 25 cases of chronic periodontitis. The CD68+ cells exhibited diffuse distribution in the connective tissue. The statistical analysis shown differences in relation to the density of this cells between the groups (p < 0,05), where the density of macrophacgic cells was higher in the chronic gingivitis. Its results can infer that the macrophagic cells has greated role in the pathogenesis of gingivitis.

Keywords : periodontal disease; chronic gingivitis; chronic periodontitis; immunohistochemical; macrophages.