Resumo

RIBEIRO, Evandro L et al. Cepas gigantes de candida albicans y su potencial de expresión/ fenotípica en niños portadores del sindrome de down. Acta odontol. venez [online]. 2006, vol.44, n.1, pp.47-50. ISSN 0001-6365.

Children with Down’s syndrome, besides the predispose factors to buccal candidiasis, present chromosomal alteration that affects the anatomic structure of the mouth and commits the immune system. In this study 30 strains of C. albicans isolated of the children's mouth were used, being 25 (83.3%) bearers of Down’s syndrome and five (16.7%) without it. This evidence turns the children with Down’s syndrome more carried of yeasts of Candida therefore predisposed the buccal candidiasis. The topographical study of the gigantic colonies of C. albicans, isolated of the children's buccal cavity with and without Down’s syndrome showed the same macroscopic aspects with prevalence of colonies with fringed periphery demonstrating that this syndrome presumably doesn't interfere in this characteristic of the  fungal colonies however this outlying colonial aspect propitiates larger capacity of adherence of strains of Candida with the injured mucous membrane and the sequels propitiated by the Down’s syndrome inducing larger favoring the buccal infection to Candida.

Palavras-chave : Buccal candidiasis; Candida; albicans; Down’s syndrome.