Abstract

GUERRA, ME et al. Multifocal epithelial hyperplasia in venezuelan indigenous children. Acta odontol. venez [online]. 2007, vol.45, n.3, pp.426-428. ISSN 0001-6365.

ABSTRACT Multifocal epithelial hyperplasia (MEH) is a disease characterised by multiple papules on the oral mucosal. MEH has been reported in American Indigenous, as well as in Eskimos and its aetiology has been related to HPV infection. Lesions typically appear in children and show a limited and benign course. The present study was carried out in six Venezuelan Indigenous communities of Gran Sabana, Bolivar State. The aim of the study was to determine the presence of MEH, describe it and eventually treat the disease. 250 children were evaluated and 18 showed HEM features (7.2%). A female predilection was observed (2:1) and the mean of age was 8 years old. Lesions were the same colour of the mucosa or slightly whiter, probably due to chewing or trauma. Lips were more frequently affected.  All cases showed histopathological characteristics of MEH, including features consistent with HPV infection. Patients were successfully treated by cryosurgery

Keywords : Multifocal epithelial hyperplasia; children; HPV.