Abstract

MORET, Yuli; RIVERA, Helen  and  GONZALEZ, José María. Correlación clínico - patológica de lesiones diagnosticadas inicialmente como leucoplasia bucal y el diagnóstico histopatológico de displasia epitelial en una muestra de 11.250 pacientes adultos: Facultad de odontología. U.C.V. Acta odontol. venez [online]. 2008, vol.46, n.3, pp.265-268. ISSN 0001-6365.

Oral Leucoplakia (OL) is a term used to describe predominantly white lesions of the oral mucous which cannot be characterized as other specific lesions and which have a potential for malignant transformation. OL is recognized as a lesion with the histopathological characteristics of epithelial dysplasia. The proportion of epithelial dysplasia (ED) which progress to spin cellular carcinomas varies within a range of 6.6% to 36 %. The purpose of this study was to determine the relationship between ED of the oral mucous clinically diagnosed as Leucoplakia. To that end a total of 11,250 micro histories were reviewed, representing all the samples analized from October 1968 to December 1998. It was found that 180 of these cases reflected the pathology of interest. These data were analyzed according to their anatomical location, sex, age, ethnic group, and degree of epithelial dysplasia. 180 cases represented oral Leucoplakias with differing degrees of dysplasia, of which 97 (52.8%) were mild ED, 67 (37. 2%) were moderate ED and 18 (10 %) were severed ED. The most frequent anatomical location reported in this study was the mucous of the alveolar ridge, with 42 cases (24. 1%). Next came and the cheek mucous, with 35 cases (19.2 %). The leading age group was 50 - 59 years (30.2%) Females had a higher predisposition with 102 cases (56.4%). The Caucasian ethnic group was the most frequently affected, with 98 cases (53.8 %). 43 % of the patients were reported to be smokers. A clinical - pathological correlation of the cases reviewed in this study shows that Leucoplakia is most often related to histopathological diagnosis of mild dysplasia.

Keywords : Correlation clinical pathological; Leukoplakia; Epithelial Dysplasia.