Resumo

ORELLANA, Alejandra; SALAZAR, Esmeralda  e  DEL VALLE, Sol. Eficacia de la clindamicina como antibioticoterapia profiláctica en la cirugía de los terceros molares. Acta odontol. venez [online]. 2009, vol.47, n.3, pp.36-45. ISSN 0001-6365.

The use of the prophylactic therapy in healthy patients under surgery oral procedures is still controversial. In accordance to the American Academy of Cardiology, penicillin continues to be the antibiotic of choice for patients who are to undergo certain dental procedures as a third molars extraction. For patients allergic to penicillin, the antibiotic of choice is Clindamycin. The aim of this study was to determine the effectivity of the clindamycin as a prophylactic therapy in the surgery of  third molars. We included ramdonly 90 patients who required third molars extraction from the School of Dentistry, Universidad Central de Venezuela distributed in six groups of 15 patients. The individuals in the drug treatment A group received 2 capsules of 300 mg of Clindamycin (DalacinÒ) to be used one hour before surgery. The A1 group received 4 capsules of 500 mg of Amocicillin  (TrimoxalÒ) to be used 1 hour before surgery. The B group received a prophylactic regimen of 12 capsules of Clindamycin orally, 1 capsule every six hours, starting one hour before surgery, until 3 days after third molar extraction. The B1 group received 21 capsules of  Amoxicillin 500 mg (TrimoxalÒ) to be administered 1 capsule every 8 hours, orally for 7 days after surgery. C and C1 groups were control groups who did not receive any type of prophylaxis . Aditionally all the groups received as a analgesic and antiinflamatory therapy, Ibuprofen (MotrínÒ) orally every six hours for 3 days. We evaluated some variables including presence of pain, exudate, infection. Ours results demonstrate that the Clyndamycin had the same efficacy than the Amocicillin for all the groups. We recomendad the administration of one dose of Clindamycin as the antibiotic prophylaxis in the third molar extractions in patients allergic to penicillin.

Palavras-chave : Clindamycin; Penicillin; allergy to Penicillin; prophylactic therapy.