Abstract

MARTINOVIC G, Gonzalo; PLAZA A, Carlos  and  SIERRA G, Andrea. Use of intralesional corticoids in focal chronic langerhans cell histiocytosis: A case report. Acta odontol. venez [online]. 2009, vol.47, n.4, pp.287-294. ISSN 0001-6365.

The term Histiocitosis of Langerhans's cells (LCH) covers a group of diseases that are the result of an alteration to the mononuclear phagocyte system. According to the clinical findings, the HCL is classified in three groups for predictable and therapeutic purposes: 1.- Focal Chronic, in general a lone injury of a bone, without affecting other organs or soft parts (Ex-Eosinophilic granuloma); 2.-Spread Chronic, (ex-Hand-Schuller-Christian); 3.- Spread Acute (ex-Letterer-Siwe).The etiology of this group of injuries remains unknown, eventhough it has been proposed: infection, inflammation and immunological reactions. Here, we present a clinical case: A 12-year-old female patient that consults for increase of volume in mandibular right back area, with a one month of evolution, not painful. Panoramic radiograph  and TAC images are showing, observing destruction of vestibular and lingually bone. The biopsy was submitted to immunohystochemical study, giving the diagnosis of Chronic Focal LCH, it was treated with Triancinolona 40 mg (Kenalog - 40) in 2 doses, after 3 years of following up there is not signs of recurrence at the date

Keywords : Langerhans Cell Histiocytosis; Eosinophilc Granuloma.