Resumen

HIDALGO, Glida et al. Determination of roc curves for the study of cut-off levels for waist circumference in pediatric population of three regions of venezuela assessed in the SENACREDH. Arch Venez Puer Ped [online]. 2011, vol.74, n.3, pp.95-99. ISSN 0004-0649.

Background: In the context of the Second National Study on Human Growth and Development of the Bolivarian Republic of Venezuela (SENACREDH), for the first time and within official and nationally representative data, ROC curves have been established for waist circumference in a pediatric population. Objectives: Determinate cut-off levels for waist circumference using ROC curves, in a pediatric population. Methods: Risk factors for metabolic syndrome were evaluated in 4,387 individuals, 5 through 19.99 y-old of the regions: North Central Coastal, Orinoco and Andean (11 states). They represented in the weight of data 1,066,864 pop. With those data a multiple linear regression model for those variables of higher importance explaining waist circumference, was validated. Then, using them jointly as defining for metabolic syndrome risk when more than one of them was present, we used them as dependent variable in order to generate ROC curves and its coordinates for the waist circumference (WC). Results: From the total of children and adolescents, 54.80% were males and 45.20% females. Mean waist circumference was 66.896 cm. (±10.49 cm., range 44.4 through 127.2 cm., p25=59.5 cm., p50=65.7 cm., p75=72.8 cm.). Mean values of WC (±DE) increased with age, in both genders, and were significantly associated at the multiple linear regression model, regard the coefficients, with fat area (ag) (p<0.001), HDL cholesterol (hdl) (p=0.005), weight (p<0.001), triglycerides (trig) (p=0.004), sum of skin-folds (sdp) (p<0.001) and BMI (imc) (p<0.001). With one factor of the only was found 35.6%, and the rest with more than one (39.7%). Six ROC curves were generated by age and sex, observing that the cut-off points were consistent with higher values in males than in females and at higher ages. Conclusions: These first ROC curves allow to establish the basement for the standardized definition of desirable and non-desirable waist circumference values in the study population and in a preliminary form, what will be defined for the country when the SENACREDH is concluded (December 2011) and published in 2012.

Palabras clave : waist circumference; metabolic syndrome; population studies; social pediatrics; Venezuela.