Resumen

FRANCO-SOTO, Vicente et al. Impact of the vaccination against rotavirus on morbidity and mortality in diarrhea. Arch Venez Puer Ped [online]. 2013, vol.76, n.3, pp.93-98. ISSN 0004-0649.

Introduction. Venezuela included rotavirus vaccine from the year 2006. Tachira State has reached 60% average coverage. The objective was to assess the impact of vaccination against rotavirus diarrhea in children under 5 years, Táchira State, Venezuela, during the years 2000-2012. Methods. Evaluation of the impact of the vaccine anti-rotavirus epidemiological study on the rates of mortality and morbidity by diarrhea. Results. There was a trend to decrease morbidity and mortality in the period 2000 to 2012, especially under the age of 1 year. The difference between average death rates between the prevaccination period (2000-2005) and postvaccination period (2006-2012) was statistically significant for children under 1 year (p=0.01;CI 95%: 4322.2-12537.1). During the prevacunal period (2000-2005), the average rate of cases per 100,000 in children under 5 years was 12,207.7 and postvacunal period (2006-2012) was 10,126.3. The difference in deaths in children under 5 years was 72 (CI 95% 62-81). Conclusions. The vaccination against rotavirus has a favorable impact on reducing rates of diarrhea in children under 5 years, particularly in the group of children under 1 years. It is an effective strategy in the prevention of deaths from this cause in under-five population.

Palabras clave : Rotavirus; immunization; deaths; child; latinoamerican.

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