Resumo

LEON, Keyra et al. Products and effects. Arch Venez Puer Ped [online]. 2015, vol.78, n.4, pp.129-134. ISSN 0004-0649.

The therapeutic benefits and mechanisms of action of probiotics have been demonstrated, mainly systemic and at the intestinal lumen. Saccharomyces boulardii (yeast) is available in a lyophilized form and is primarily used in the treatment and prevention of diarrhea and other gastrointestinal diseases. The mechanism of action is multiple and includes modification of the host cell, the pro-inflammatory response, electrolyte secretion, immune stimulation, neutralization of toxins, reduced adherence of bacteria and inhibition of translocation of pathogens. Lactobacillus present in the gastrointestinal tract and vagina are Gram positive bacteria that produce lactic acid as a major fermentation product. Bacillus clausii, spore-forming Gram positive, produce beneficial effects in the gastrointestinal tract, through the release of antimicrobial compounds and modulating immune activity, increasing the production of secretory immunoglobulin. The pharmacological effects of these probiotics, are specific strain, so its selection should be based according to their demonstrated effects.

Palavras-chave : mechanism of action; probiotics; kids; adolescents.

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