Abstract

ARREDONDO, C et al. Fibrosis quística y colonización bacteriana del tracto respiratorio. Gen [online]. 2006, vol.60, n.3, pp.167-170. ISSN 0016-3503.

Cystic fibrosis is a genetic disorder due to a mutation in chromosome 7, which codifies the protein (CFTC) that takes part in the ion transport in the epithelial cells. The pulmonary infections are caused by a great variety of unusual germs; that complicate and prolong its development. The objective of the present study was to acknowledge the presence of germs in respiratory tract of the patients with CF with manifestations of pancreatic insufficiency and different nutritional states. 68 histories of patients with diagnosis of CF controlled at the Service of Gastroenterology of the J.M. de los Rios Hospital were reviewed., 45/68 (66.2%) were male and 23/68 (33.8%) female. 28/68 patients were excluded in which we did not know the reports of the bacteriological study. In 30/40 patients had microbial growth in airways; mainly Pseudomona aeruginosa 15/30 (50%) and Staphylococcus aureus 15/30 (50%). At the moment from a nutritional point of view 9/30 (30%) are at the critic zone, 7/30 (23.2%) normal and 6/30 (20%) show serious undernourishment. The correlation between isolated germ and nutritional state was not statistically significant (p>0.5). In conclusion, respiratory infections in patients with CF of mixed affectation are caused by colonization of opportunistic germs causing progressive pulmonary damage, independently of the nutritional state, requiring opportune aggressive respiratory and nutritional handling.

Keywords : cystic fibrosis; isolated germs; respiratory infections.

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