Abstract

MARTINEZ, Yolette et al. Esofagitis por reflujo no erosiva: Correlación clínico-morfológica. Reporte preliminar. Gen [online]. 2008, vol.62, n.4, pp.294-295. ISSN 0016-3503.

We carried out a descriptive study with 20 patients with typical GERD symptoms (heartburn and regurgitation) with a normal upper endoscopy. Histological alterations in esophagitis are: basal cell hyperplasia, papillomatosis, acanthosis and dilation of intercellular spaces. We found in 45 % of the cases histological alterations compatible with GERD. This technique, can evidence the usefulness of biopsies, in patients with GERD, when biopsy samples are taken one centimeter above the Z-line. In a future study we will compare these findings with patients who have typical symptoms of GERD with erosive esophagitis and a control group.

Keywords : histological alteration; non erosive esophagitis; heartburn; regurgitation.