Abstract

GUGGISBERG, Wilhelm et al. Adenocarcinoma gástrico y gastritis quística profunda en una paciente con historia de gastritis crónica y uso continuado de aines. Gen [online]. 2009, vol.63, n.1, pp.60-61. ISSN 0016-3503.

We present a case of a 70 years old female patient with active chronic gastritis (ACG), chronic use of NSAIDs and pyloric stenosis. After a simple subtotal gastrectomy, a stenosing, well differentiated Adenocarcinoma at the antrum and pylorus was unexpectedly found, with infiltration to the perigastric soft tissues and the distal resection margin; as well as gastritis cystica profunda (GCP) at the antrum and pylorus with dysplasia, mixed with the tumor, and multifocal GCP. There are only 4 cases published where the coexistence of GCP with gastric adenocarcinoma are described (only 2 with direct association). This is the only case which describes thus far the association of these two entities with chronic use of NSAIDs. This reinforces the idea that such a premalignant condition is not necessarily related only to previous post-surgical gastric conditions, but also to other mucosal deleterious agents such as NSAIDs.