Resumen

LANDAETA, Neyda et al. Screening para enfermedad celiaca en familiares de primer grado de niños celiacos. Gen [online]. 2009, vol.63, n.2, pp.108-110. ISSN 0016-3503.

Celiac disease is an autoimmune enteropathy induced by the gluten from the diet, with variable involvement of intestinal epithelium and broad clinical spectrum. Objective: To determine the presence of serological markers for Celiac Disease in first degree relatives of celiac children. Material and Methods: Serological determinations of Antitransglutaminasa IgA and Antiendomisysium IgA (EMA) were performed in first degree relatives of 7 children with Celiac Disease. Results: We studied 16 families between 15 to 51 years with an average age 33.7 years. 6 / 16 (37.5%) were positive for Antitransglutaminasa IgA and 9 / 16 (56.25%) were positive for EMA. Of the relatives who presented positive screening 4/10 (40%) presented signs or symptoms that could be associated with Celiac Disease, such as: diarrhea, abdominal distension and pain; 6/10 (60%) of patients were asymptomatic. Conclusion: We reported 10 cases of relatives of celiac children with positive serology for the disease. Given the susceptibility of this group we considered and alerted the research of this entity in relatives of patients with celiac disease. Keys Words: First degree relatives, Celiac Disease, Children, Antitrastaminase IgA, Antiendomisysium IgA.

Palabras clave : Familiares de 1er grado; Enfermedad Celiaca; Niños; Antitransglutaminasa IgA; Antiendomisio IgA.