Abstract

ARMANIE, Emma et al. Hallazgos clínicos, endoscópicos e histológicos asociados a la infección por Helicobacter pylori considerando los genotipos CAG A y VAC A en pacientes con dispepsia: Servicio de Gastroenterología. Hospital Central Universitario “Antonio María Pineda”. Barquisimeto estado Lara. Gen [online]. 2010, vol.64, n.2, pp.76-81. ISSN 0016-3503.

Dyspepsia affects quality of life for many patients and often is associated with Helicobacter pylori infection. This bacterium is recognized as the causative agent of chronic gastritis, is associated with development of gastric and duodenal ulcers and, with the development of gastric cancer. Primary objective was raised to establish the clinical, endoscopic and histological findings associated with Helicobacter pylori infection considering genotypes cag A and vac A in patients with dyspepsia who attended the Gastroenterology Service of Hospital Central Universitario “Antonio María Pineda”. This is a cross-sectional descriptive epidemiological study. The population consisted of patients with dyspepsia who attended the gastroenterology service. The sampling was intentionally non-probabilistic, since we only took the people who consulted with dyspeptic symptoms and met the established criteria of inclusion and exclusion. These patients were questioned about dyspeptic symptoms, underwent upper gastrointestinal endoscopy, endoscopic findings were described and samples were taken for histology and genotyping. We found an incidence of H. pylori of 98.5%, infection prevailed in females, the genotypes cag A positive and m1/s1 allelic forms are most frequent in the population studied and, the same is associated with chronic gastritis, gastric ulcers and intestinal metaplasia incomplete.

Keywords : clinical findings; endoscopic findings; histological findings; Helicobacter pylori genotypes; Dyspepsia.