Abstract

MEDINA, Marco et al. Síntomas gastrointestinales y hallazgos de endoscopia digestiva superiror en niños con insuficiencia renal crónica terminal: Hospital "JM de los Ríos" Caracas, Venezuela. Gen [online]. 2010, vol.64, n.3, pp.174-179. ISSN 0016-3503.

Patients with Stage 5 Chronic Kidney Disease (CKD), known as end-stage renal disease (ESRD), may manifest a variety of gastrointestinal lesions and suffer complications. Objective: To investigate the clinical and endoscopic findings in pediatric patients with this condition. Patients and Methods: Over a period of 5 years (January 2004 to December 2008), the patients were evaluated in the pediatric gastroenterology service by upper gastrointestinal endoscopy before kidney transplant. Results: We studied 75 patients: 37 female and 38 male, with a mean age of 12 years-old; 42.7% were asymptomatic and 57.3% experienced symptoms: heartburn (23.2%), reflux (23.2%), abdominal pain (18.6%), abdominal distension (14%), vomiting (9.3%), nausea (7%) and hematemesis (4.6%). Endoscopy reported normal in 18 patients (24%) and the remaining study was abnormal: erosive gastropathy (43.9%), duodenitis (24.5%), nodular gastropathy (14%), esophagitis (14%) and hiatal hernia (3.5%). Presence of Helicobacter pylori (22.7%). Conclusions: We determined that endoscopic evaluation should be included in patients with pre-renal transplant protocol, since they have various gastrointestinal disorders that may influence the evolution and prognosis of the transplant.

Keywords : gastrointestinal symptoms; end-stage chronic renal failure; upper gastrointestinal endoscopy.