Abstract

RUIZ, María Inés. Respuesta a la terapia combinada vs monoterapia con betabloqueantes en profilaxis primaria de sangrado variceal en pacientes con cirrosis hepática. Gen [online]. 2011, vol.65, n.3, pp.187-193. ISSN 0016-3503.

This research was aim to relate the results propranolol combined or not with endoscopic ligation (LE) in the primary prophylaxis of variceal bleeding in the Gastroenterology Service, Hospital Universitario de Maracaibo, during the months of January to October 2009. A correlational, prospective, longitudinal type study. The population was 40 patients between 18 and 75 years old with liver cirrhosis and esophageal varices of large-medium size, with no history of upper gastrointestinal bleeding. They were two randomly selected samples, the first is represented by 20 patients who underwent LE combined with propranolol and the second 20 patients treated with propranolol alone. For data collection a questionnaire was designed based on the variables, dimensions and indicators proposed in the research. We demonstrated that monotherapy with propranolol is as effective as combined with LE in the primary prophylaxis of variceal bleeding.

Keywords : Liver cirrhosis; Esophageal varices; Primary prophylaxis; Treatment; Propranolol - endoscopic ligation.