Abstract

DE OLIVAL, Carmen et al. Pseudopapillary tumor of pancreas:: a solid infrequent tum. Gen [online]. 2012, vol.66, n.1, pp.49-52. ISSN 0016-3503.

Introduction: the pancreatic pseudopapilar tumor or Frantz’s tumor was described for the first time by Gruber Frantz in 1959, and represents less than 1% of the pancreatic neoplasia. It is more frequent in young women, between the second and third decade of life, even though it has also been described in men, with a women:men relationship of 1:10. Objective: evaluate during one year the frequency of pseudopapillary tumors of pancreas, and their clinic, ultrasonographyc and cytological features. Design: it is a descriptive and retrospective study, carried out from March 2010 to March 2011. We used an Olympus GF-UM130/Q130 endoscopic ultrasound equipment with Aloka software. Results:2 cases were found (0.94%) in a total of 212 endoscopic ultrasounds of gallbladder and pancreas. Both cases were females of 16 and 44 years old, with clinic manifestations of acute pancreatitis and digestive bleeding, respectively. The lesions were heterogeneous, with variable diameters from 4.60 to 7.25 cm, making contact with the upper mesenteric vein, displacing it to the periphery, along with an enlarged and tortuous Wirsung conduct. Puncture and aspiration with a 22G needle and the appropriate serohematic content, were the procedures performed to the patients, being one of them mainly hematic. The samples were evaluated by a pathologist expert in cytopathology. Conclusion: the tumors of the pancreas were identified as well defined masses, encapsulated, with a mix solid-cystic appearance, which cause displacement of adjacent structures without invading them. This neoplasia had slow growth, indolent development and no constitutional alterations. Puncture of the tumors with a fine needle and their cytopathologic evaluation were basic tools to study this neoplasia, since they allowed us to identify branched papilla with mix fibrovascular stroma and monomorphic tumor cells, with round nucleus and foamy cytoplasm. The treatment of choice was surgical resection, such as reported in literature. It has achieved a 97% survival rate to the second year with a recurrence probability of 2-6%.

Keywords : pancreas; neoplasia; ultrasonographyc endoscopy.