Abstract

DE FARIA, Alejandro; CASANOVA, Gerardo; MILANO, Melise  and  TORRES, Adrian. Relationship between histology and the test of quantitative breath in gastritis follicular (helicobacter pylori), Mucuchies - Mérida. Gen [online]. 2012, vol.66, n.3, pp.166-170. ISSN 0016-3503.

Introduction: Helicobacter pylori is a microaerofilic bacile asociated to follicular gastritis in 95% of the cases and to gastric cancer in 60-70%. In Venezuela, its prevalence reaches 62%, while in Mucuchies, Merida it is 75%. General Aim: To relate the quantitative C¹⁴ urea breath test with the histology in H. Pylori’s follicular gastritis in Mucuchies. Methods: There was a sample of 100 individuals between 18 and 50 years, selected from probabilistic stratified sampling. Results: The H. pylori prevalence was 76%. The C^¹4 urea breath test had a sensitivity of 90%, a specificity of 75%, a PPV of 86% and a NPV of 82% in the diagnosis of follicular gastritis. The 84,1% of the cases of follicular gastritis was asociated with gastric atrophy. The Spearman correlation between the cuantitative value of the urea breath test with the inflammation grade was -0,550; with bacterial density 0,792 and the relation between density and inflammation grade was -0,454. All these values were estadistically significatives. Conclusion: the cuantitative value of the C^¹4 urea breath test is proportional to the inflammation grade and H. pylori density in the follicular gastritis, which is asociated with gastric atrophy, preneoplastic condition to adenocarcinoma development.

Keywords : Gastritis Follicular; H. pylori; The C¹4 Urea breath.