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Abstract

ACOSTA, Marthelena; MEJIAS, Luis  and  RUIZ, María. Morphologic spectrum of liver biopsy. Gen [online]. 2013, vol.67, n.1, pp.4-10. ISSN 0016-3503.

Introduction: liver biopsy is an excellent diagnostic method in the spectrum of liver pathology. For some authors liver biopsy is considered the "best method" due to sampling error and interobserver variations, however is still considered by many the "method of choice". Sample and Methods: We collected and analyzed retrospectively, the histological preparations and request ballots biopsies of all cases of liver biopsies, from the Section of Gastrointestinal and Liver Pathology "Dr. Pedro Grases "Institute of Pathology" Dr. José A. O’Daly "Central University of Venezuela, in the period between January 1996 and December 2006. Results: 50.8% patients were female and 46.8% male. The most affected age group (55.4%) was between 31 and 60 years. The most frequent clinical findings were jaundice (7.9%) and right upper quadrant pain (5.3 %). Frequency of histopathological diagnoses: steatosis (15.1%), hepatitis C virus (12.3%), metastatic tumors (8.9%), cirrhosis (8.1%), steatohepatitis (6.7%), vascular diseases (5.4%), primary liver tumors (4.1%). Conclusions: Liver biopsy is an excellent tool for diagnosis and treatment, if you do a good clinicopathologic correlation.

Keywords : jaundice; biopsy; hepatitis; steatosis; steatohepatitis; cirrhosis; clinicopathologic correlation.

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