Abstract

CASTRO, Ibrahim  and  MARTINEZ, Mariano. Biliary lipids transporters: an update review. Gen [online]. 2013, vol.67, n.1, pp.49-57. ISSN 0016-3503.

Bile salts, cholesterol and phosphatidylcholine are the major lipids of bile; its secretion is regulated by an elaborate network of family proteins such as ATP Binding Cassette and the Solute Carrier. Biliary lipids transporters are proteins involved in physiopathology of many diseases of gastrointestinal system, therefore it are important molecules of study and the future it may be new therapeutic targets to prevent the prevalence of diseases, such as hypercholesterolemia, gallstones, cholestasis, bilirubin disorders among other. This review makes a current evaluation on the specific role of biliary lipids transporters, its genetic regulation and physiopathological implications.

Keywords : biliary lipids; transporters; gastrointestinal system; therapeutic target.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )