Abstract

PEREZ, Honey et al. Gastroomtestinal stromal tumor (GIST) in jejunum: Report of a case. Gen [online]. 2013, vol.67, n.4, pp.233-235. ISSN 0016-3503.

GISTs originate from the interstitial cells of Cajal. Report the case of male patient 65 years old with a history of upper gastrointestinal bleeding in two occasions (July 2011 and September 2011) with upper and lower gastrointestinal endoscopy without pathological findings, who present on December 27th 2011 four occasions, later, generalized weakness and dizziness why go to Dr. Miguel Perez Carreno hospital, which evaluation and admitted to hospital. Physical exam: TA: 130/70 mmHg. FC: 90 LPM FR: 20 RPM. Patient in stable general condition, afebrile, dehydrated, eupneic. Skin: pale skin and mucosa moderate. Abdomen: soft, depressible, painless on palpation, bowel sounds present. DRE mane. Laboratory: Gb: 21.900, 82% N Hg: 4,6 Hct: 15,8 % Plt: 176,000. Upper and lower endoscopy are normals limits. Intestinal transit was performed demonstrating Jejunum default image. TAC Abdomino - reported double-contrast pelvic wall thickening of the intestinal loop, distal jejunum with changes in density of peripheral fat may correlate with tumor vs inflammatory process. Laparotomy was performed and infraumbilical supra trans with tumor findings 8 x 6 cm pedunculated born in the mesentery compressing face jejunum mesenteric fixed handle 140 cm bleeding. Biopsy was performed and immunohistochemical piece reporting gastrointestinal stromal tumor spindle cell pattern of high risk. CKIT: positive, negative actin, S100 protein: positive isolated, KI 67: 30% positive, CD34: positive. Imatinib treatment was indicated. We conclude that the presence of occult bleeding is imperative that comprehensive studies to arrive at an accurate diagnosis and give the patient the best therapeutic tools in favor of the resolution of the pathology.

Keywords : GIST; Jejunum; Imatinib.

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