Introduction:

Appendicitis is one of the leading causes of acute abdomen. Conventional surgical treatment is not exempt from complications, which has driven the development of Endoscopic Retrograde Appendicitis Therapy (ERAT) as a minimally invasive and organ-preserving alternative.

Materials and Methods:

A retrospective case series was conducted in six patients with either uncomplicated acute or chronic appendicitis who were treated with ERAT between July 2024 and July 2025. Endoscopic findings, clinical outcomes, pain (as measured by the Visual Analog Scale, or VAS), patient satisfaction, and adverse events were evaluated.

Results:

In this preliminar series of cases the mean age was 37 years (66.6% males). The most frequent endoscopic findings were congestive mucosa (100%) and purulent secretion (83.3%). A plastic stent was placed in 83.3% of cases, with subsequent spontaneous expulsion. No complications or adverse events were recorded. Pain levels decreased from a mean VAS of 5.67 to 2.33; 83,3% of patients resumed daily activities in less than 48 hours, and hospital discharge was immediate in all cases. The mean satisfaction score was 4.0. No recurrences were observed at six months.

Conclusion:

ERAT has proven to be a safe, effective, and rapidly recovering technique that allows for appendix preservation. The findings of this preliminary series support its feasibility and justify prospective multicenter studies.