Abstract

PENA-MARTI, Guiomar et al. Asociación entre prematuridad y embarazadas en edad avanzada. Rev Obstet Ginecol Venez [online]. 2007, vol.67, n.1, pp.15-22. ISSN 0048-7732.

Objective: To determine the association between prematurity and 35 years old pregnant women or more. Method: The sample was of 1 863 pregnant women (Cases: 620, Controls: 1 243). The exposition variable was age ≥ 35 years old and of the outcome variable was prematurity (gestation < 37 weeks, according to OMS). For determination of the parsimonious model the likelihood ratio test was used. Setting: Ciudad Hospitalaria “Dr. Enrique Tejera” and Maternidad del Sur, Valencia. Results: Crude evaluation of the association showed an odds ratio (OR) of 2.07 (IC95 % = 1.6 to 2.6; P = 0.00001). Multiparity conditioned modification of the effect. Nuliparous older pregnant women has a higher risk of prematurity (OR = 4.5; IC95 % = 1.3 to 15.5; P = 0.01). On the contrary, in the older multiparous pregnant women, the association was no statistically significant (OR = 1.3; IC95 % = 0.8 to 2.1; P = 0.1). Conclusions: Pregnancy in older women has an increase risk of preterm labor and this risk increase if the woman is primigravida.

Keywords : Prematurity; Older pregnant woman; High risk pregnancy.