Abstract

IGLESIAS, Marylin; SAMOROO, Juan; CASANOVA, Eduardo  and  UZCATEGUI U, Ofelia. Parto pretérmino: valor predictivo del estriol salival, vaginosis bacteriana y longitud cervical. Rev Obstet Ginecol Venez [online]. 2007, vol.67, n.3, pp.143-151. ISSN 0048-7732.

Objective: To evaluate the salivary estriol concentration, presence of bacterial vaginosis and cervical length as predictors of preterm labor in asymptomatic patients. Methods: Descriptive, prospective and comparative study, in pregnant patients divided into two groups. The study group (A) and the control group (B). Setting: Outpatient prenatal clinic at the "Hospital General del Oeste "Dr. Jose Gregorio Hernandez". Results: From 60 patients evaluated, 5 (8.33 %) had preterm delivery, 4 (80 %) belong to the group A and 1 (20 %) to the group B. The last one was induced by medical reasons. There were 3 cases (5.0 %) of threatening of preterm delivery from the group A. In the patients with preterm delivery the length of the uterine cervix between 16 to 18 weeks of gestation ranged from 30 to 45.6 mm with mean of 38.05 ± 6.38 mm. Between the 24 and 28 weeks the values were between 24 and 25 mm with mean of 24.78 ± 0.68 mm. In the patients with preterm delivery the bacterial vaginosis between 16 and 18 weeks was present in 3 patients; between 24 and 28 weeks all patients had positive results. The concentrations of free estradiol in saliva in patients with preterm delivery ranged from 0.3 to 3.5 ng/mL, with a mean of 1,55 ± 1,45 ng/mL. At 29 weeks from 0.8 to 3.7 ng/mL, mean 1.73 ± 1.0 and at 36 weeks from 2.3 and 3.2 ng/mL with mean of 0.85 ± 1.10 ng/mL. Conclusion: The shortening of uterine cervix (lower or equal to 25 mm) determined by transvaginal ultrasound between 24 and 28 weeks, is significatly associated to preterm delivery in asymptomatic patients with high risk. On the other hand, the increase of free estriol in saliva is not significantly associated to preterm delivery in these patients. Bacterial vaginosis was observed more frequently in patients with high risk of preterm delivery

Keywords : Preterm delivery; Uterine cervix length; Estriol in saliva; Bacterial vaginosis; Transvaginal echosonogram.