Resumen

CHACIN PENA, Belkys. Citología endometrial en pacientes posmenopáusicas con terapia hormonal. Rev Obstet Ginecol Venez [online]. 2008, vol.68, n.2, pp.73-80. ISSN 0048-7732.

Objective: To demonstrate the efficacy of endometrial cytology with the Uterobrush® sampler and compare it with endometrial biopsy, in postmenopausal women under hormonal replacement therapy. Method: Prospective study with 30 patients during a lapse of six months, fifteen of them refered abnormal uterine bleeding and the other fifteen did not. Endometrial cytology sampling was done with Uterobrush® and biopsy with Novak´s currette to all patients. Difficulty, pain, bleeding, cervical characteristics, celularity and adequacy of the sampling where assessed, cytology was compared with biopsy diagnosis. Setting: Gynecology service of the University Hospital of Los Andes, Results: 73.3 % of the patients did not refer pain. No bleeding was present after the introduction of Uterobrush ® in 53.3 %. The samples were adequate in 70 % of cases. Principal cause of limitation was poor fixation of cells. When comparing cytologic diagnosis with biopsy we found a sensitivity of 71 % and 75 % specificity. Conclusions: The endometrial cytology with Uterobrush® is a procedure easy to use, economic, and well tolerated by the patients; being useful to evaluate the endometrium in post menopausal women, but not pretending to overtake endometrial biopsy.

Palabras clave : Endometrial cytology; Endometrial biopsy; Postmenopause.