Resumen

ALARCON DE NOYA, Belkisyolé et al. Despistaje de toxoplasmosis y enfermedad de Chagas en la Consulta Prenatal del Hospital Universitario de Caracas. Rev Obstet Ginecol Venez [online]. 2010, vol.70, n.2, pp.75-81. ISSN 0048-7732.

Objective: To determine seropositivity for Toxoplasma gondii and Trypanosoma cruzi in pregnant women. Methods: A cross-sectional analytical study was conducted at 678 pregnant women. ELISA was used for the detection of anti-Toxoplasma antibodies IgM, IgG and IgG avidity. For T. cruzi IgG ELISA was performed and Indirect Hemagglutination Test. Setting: Prenatal care at the Hospital Universitario de Caracas. Results: The highest number of patients was located in the age group 16 to 20 years, 42 % was in her first pregnancy, 25 % the second and 33 % had 3 or more. The 39 % was in the first trimester, 43 % in the second and 18 % in the third. The screening for T. cruzi showed no reactive person. Toxoplasmic infection was presented by IgG ELISA in 38 % of pregnant women of which 10 might be due to recent infections by having a positive IgM or low avidity of specific antibodies, 8 of them were in the first or second trimester of pregnancy. A second serology in 54 women did not show seroconversion. Conclusions: Toxoplasmosis seropositivity was high and detected some pregnant women with recent infection in the first two quarters, when there is risk of congenital malformations. The combination of these techniques in Toxoplasmosis can estimate time of evolution and its application in prenatal consultations would detect recent infections. It is equally important to emphasize the obligation of the diagnosis of Chagas’ disease which can be transmitted to the fetus and also because Venezuela is an endemic country.

Palabras clave : Toxoplasma gondii; Toxoplasmosis; Chagas´disease; Pregnancy; Diagnosis; Venezuela.