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Revista de Obstetricia y Ginecología de Venezuela
versión impresa ISSN 0048-7732
Resumen
SANTOS-BOLIVAR, Joel et al. Legrado uterino o nifedipina durante el posparto en pacientes con preeclampsia severa. Rev Obstet Ginecol Venez [online]. 2011, vol.71, n.4, pp.240-245. ISSN 0048-7732.
Objective: To compare the efficacy of uterine curettage or nifedipine during postpartum in patients with severe preeclampsia. Setting: Maternidad Dr. Nerio Belloso, Hospital Central Dr. Urquinaona, Maracaibo. Estado Zulia. Methods: A research was done in 60 patients with diagnosis of severe preeclampsia that were divided of following way: group A (n = 30) who were submitted to uterine curettage and group B (n = 30) who received nifedipine (10 mg orally every 8 hours x 24 hours). Blood pressure changes, platelet count, laboratory parameters and adverse effects were evaluated. Results: Maternal age, gestational age at the moment of delivery and type of delivery were similar to patients of group nifedipine and patients of uterine curettage group (p = ns). There were not significant differences in mean values of systolic blood pressure, diastolic blood pressure and platelet count between groups (p = ns). There was also not significant differences between groups in initial and at 24-hours values of hemoglobin, hematocrit, bilirubin and transaminases (p = ns). The only adverse effect that presented a significant difference and a high incidence was headache in group of severe preeclamptic patients treated with nifedipine (26 cases; P < 0.05). Conclusion: Nifedipine is as effective as uterine curettage during postpartum in patients with severe preeclampsia.
Palabras clave : Nifedipina; Preeclampsia; Legrado uterino; Nifedipine; Preeclampsia; Curettage.