Abstract

REYNA-VILLASMIL, Eduardo et al. Perfil lipídico y malonilaldehído en preeclámpticas. Rev Obstet Ginecol Venez [online]. 2012, vol.72, n.1, pp.28-33. ISSN 0048-7732.

Objective: To determine lipids, lipoproteins, apolipoproteins and malonilaldehyde concentrations in preeclamptic and normotensive patients. Method: Seventy patients who assisted to obstetric emergency were selected and divided in two groups using a non-probabilistic sampling method. Both groups consisted in preeclamptic patients (group A) and normotensive pregnant women (group B), considered as controls. Plasma total cholesterol, triglycerides, apolipoproteins A-I and B, high density lipoprotein (HDL-C), low density (LDL-C), very low density (VLDL) and malonilaldehyde were measured. Settings: Hospital Central "Dr. Urquinaona". Maracaibo, Estado Zulia. Results: There were not significant statically differences in mean maternal age and weight between preeclamptic patients and controls (P = ns) There were found significant differences in gestational age at the moment of delivery, systolic and diastolic blood pressure, newborn weight and presence of proteinuria (P > 0.05). There were statically significant differences in concentrations of triglycerides, HDL-C, VLDL, apolipoprotein B and malonilaldehyde (P < 0.05). There were not found significant differences in plasma concentrations of cholesterol, LDL-C and apolipoprotein A-I (P = ns). There were negative significant correlations in preeclamptic between HDL-C and LDL-C and between HDL-C and apolipoprotein B (P < 0,05). Conclusions: There are significant differences in triglycerides, HDL-C, VLDL, apolipoprotein B and malonilaldehyde in preeclamptic patients.

Keywords : Preeclampsia; Triglycerides; Lipoproteins; Apolipoproteins; Malonilaldehyde.

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