Abstract

CASTILLO, María Betzabeth; GIRON, Juvenal  and  CABRERA, José Alberto. Patrón clínico en gestantes con síndrome antifosfolipídico (SAF). Rev Obstet Ginecol Venez [online]. 2014, vol.74, n.1, pp.3-9. ISSN 0048-7732.

Objective: Describe characteristics epidemiological, clinical and analytical for pregnant carrying the antiphospholipid syndrome that were treated in internal medicine, period 2001-2012. Methods: Descriptive, longitudinal, non-experimental and field study. The population that was studied in 157 patients carrying the antiphospholipid syndrome, was not taken into account the criterion interval of at least 12 weeks for definitive diagnosis. Results: We identified 143 patients as primary antiphospholipid syndrome, secondary antiphosphilipid syndrome while as 14 patients. Eighty-six patients had only positive titers of anticardiolipin antibodies, followed 62 patients with positive titers for anticardiolipin antibodies and beta 2 glycoprotein 1, 4 with anticardiolipin antibodies and lupus anticoagulant, beta 2 glycoprotein 1 positive, 3 only lupus anticoagulant positive and 2 beta 2 glycoprotein 1 only positive. The triple anticoagulant therapy with low molecular weight heparin plus acetylsalicylic acid and low-dose prednisone was the most frequently used in 99 patients. Conclusion: In addition to proper treatment, prenatal and maternal-fetal monitoring closely a favorable result was obtained for the welfare and maternal and fetal health.

Keywords : Antiphospholipid syndrome; Antiphospholipid antibodies; Anticardiolipin antibodies; Pregnancy; Recurrent fetal loss.

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