Resumen

DE GUGLIELMO, Zoraya et al. Posible transmisión vertical de virus de papiloma humano en niños cuyas madres presentan antecedentes de infección viral. Rev Obstet Ginecol Venez [online]. 2015, vol.75, n.1, pp.025-029. ISSN 0048-7732.

Objective: Detection and typing of Human Papillomavirus in samples of children whose mothers have a history associated with the virus. Methods: Transversal and descriptive study. Perianal swabs of 66 children with an average age of 18 months treated in the Service of Dermatology, University Hospital of Caracas, were processed. Viral detection was performed by PCR with MY11 and MY09 generic primers; typing of positive samples was performed by multiplex PCR. Results: A positive percentage of 54.5 % was obtained and low oncogenic risk HPV identified in 47.2 %, high-risk viral DNA in 13.88 % and mixed infections with types of high and low oncogenic risk in 5.55 % of the positive samples. 33.33 % of these samples could not be typed with the used methodology. Conclusions: Although the viral type is unknown in mothers to make comparisons with the types identified in children, these results highlight the possible vertical transmission of HPV, considering maternal history, the young age of the children and that the condition of sexual abuse was ruled out. It is recommended to monitor the studied population including the evaluation of samples obtained from the parents.

Palabras clave : HPV; Vertical transmission; Children; PCR Pregnancy; Recurrent fetal loss.

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