Resumen

SARABIA SALAZAR, Daniel; OLIVAR, Freddy Ángel; PENA CARPIO, Indira Elena  y  GONZALEZ BLANCO, Mireya. Misoprostol en la conducta activa en el tercer período del parto: dosis mínima efectiva. Rev Obstet Ginecol Venez [online]. 2015, vol.75, n.3, pp.155-163. ISSN 0048-7732.

Objective: To compare the effects of the use of sublingual misoprostol in doses of 200 μg, 400 μg or 600 μg in the active of the third period of confinement conduct. Methods: 350 patients with pregnancies to term, showing vaginal birth were included. They were distributed randomly in 3 groups (A, B and C) which received doses 200 μg, 400 μg and 600 μg of sublingual misoprostol respectively as part of conduct active during childbirth. Is recorded time between the expulsion of the newly born and full delivery, lost blood during this period, and the presence of adverse effects until the time of his graduation. Results: The average delivery time was 3 ± 0.9 minutes for the Group of 200 μg, 2.8 ± 0.7 minutes for the Group of 400 μg and 2.8 ± 0.6 for the Group of 600 μg (P = 0, 172). Reported four cases of uterine hypotonia, 1 in group A, 2 in group B and 1 in group C, and three cases of retention of remains, one in each group. Were nausea, vomiting, tremors, liquid evacuations, and fever in low percentage (less than 5 %) unrelated to the dose (P > 0.05). Conclusions: In doses of 200 μg misoprostol is as effective as doses above, conduct active birth, with one incidence of less than 1 % of postpartum haemorrhage and few adverse side effects.

Palabras clave : Childbirth; Postpartum haemorrhage; Misoprostol; Active conduct.

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