Resumen

CASTILLO, Haydee Karina et al. Papilomatosis laríngea juvenil y su relación con la infección genital por virus de papiloma humano durante el embarazo. Rev Obstet Ginecol Venez [online]. 2015, vol.75, n.4, pp.260-268. ISSN 0048-7732.

Objective: To establish the relationship between the diagnosis of juvenile laryngeal papillomatosis and genital infection with human papilloma virus during pregnancy. Methods: 18 mothers whose children’s diagnoses were juvenile laryngeal papillomatosis were included. The children’s history were checked, the mothers were given the anamnesis procedure looking for human papilloma virus infections during pregnancy, they were given actual gynecologic evaluations, citology, vulvoscopy, vaginoscopy, colposcopy and biopsy where needed. Samples were taken for their viral tipification. Results: There were 120 cases of juvenile laryngeal papillomatosis in 14400 patients, an 0.8% frecuency. Amongst the evaluated patients, most were males (61.1 %). Age at diagnosis was 5.7 ± 3.2 años. The disease had an evolution median time of 2 years. The medical intervention median per patient was 3. The most frecuent clinical manifestations were disnea (83.3 %) and dysphonia (61.1%). The viral genotype on laryngeal lesions was 6 (50%), 11 (11.11 %) and coinfection 6 y 11 (11.1 %). Human papilloma virus was detected in 5 mothers: 3 high risk and 2 non classifiable. Vaginal birth was the most frequent with an 83.3 % rate. Conclusion: Juvenile laryngeal papillomatosis is not very frequent (0.8 %), generates a manifestation of variable severity characterized by dysnea and dysphonia, produced by human papillomavirus 6 and 11 and is associated to vaginal birth. There was no correlation between the viral types of mothers and children.

Palabras clave : Juvenile Laryngeal Papillomatosis; Human Papiloma Virus; Polymerase chain reaction.

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