Resumen

PACHECO, María et al. Tipificación de virus de papiloma humano en lesiones preneoplásicas y neoplásicas del cérvix. Rev Obstet Ginecol Venez [online]. 2016, vol.76, n.1, pp.23-33. ISSN 0048-7732.

Objective: To determine the type of virus human papillomavirus by the technique of polymerase chain reaction in premalignant lesions (NIC I, II, III) and neoplastic (cancer in situ) in patients who attended the consultation cervical pathology. Methods: Not experimental and field, cross-sectional study of 102 patients with cervical pathology consultation, of which 42 patients were included in the study and, she underwent an interview and then a decision by the exfoliated cervical swab technique, which were collected in a collecting tube to be processed in the clinical laboratory and immunodiagnostic BRIMED CA by polymerase chain reaction. Results: Using polymerase chain reaction were positive for human papillomavirus 24 patients, mostly between the ages of 34 to 39 with 7 patients, genotype 6 was the most common with a total of 12 patients being the NIC I the type of neck injury more affected with 5 patients in this group, while only 10 patients tested positive for high-risk genotype, the most common being that of another genotype with a total of 7 patients, obtaining cervicitis NIC II and neck injuries as most affected 2 patients in each group. Conclusions: Human papillomavirus polymerase chain reaction technique had a sensitivity of 57.1 % and specificity of 42.9 % in this study, with the low risk genotype 6 the most common in all, the intermediate risk was common in just 2 patients and high risk, the most common was that of another genotype with a total of 7 patients, while genotype 16 was the least frequent. Likewise, the ratio of the age group human papillomavirus is frequently ranked among the ages of 34-39 years and in relation to the type of cervical lesion NIC I was the most common.

Palabras clave : Human papillomavirus; Polymerase chain reaction; Genotyping; Neoplastic; NIC; Cancer in situ.

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