Resumen

MARQUEZ C, Daniel et al. Maternal aponeurosis allograft in fetal microneurosurgery for congenital spina bifida. A new proposal about two successful cases. Rev Obstet Ginecol Venez [online]. 2025, vol.85, n.1, pp.93-101.  Epub 29-Ago-2025. ISSN 0048-7732.  https://doi.org/10.51288/00850114.

Prenatal repair of congenital spina bifida significantly reduces its comorbidity, but sometimes, primary closure of the defect is not possible, requiring tissue grafting or the use of prosthetic material. Based on clinical trials in humans with the use of maternal skin allograft as an autologous alternative, it was considered to implement a hypocellular and hypovascular tissue, rich in collagen and hyaluronic acid, with high fibroblast content, high resistance and good malleability, maternal aponeurosis, as a feasible alternative in the country, bioethically acceptable, easily obtainable and at zero cost. We present the immediate postnatal result and follow-up during the first 60 days of life of two cases of fetal microneurosurgery with placement of maternal aponeurosis allograft. The success obtained in both cases could be considered as the formal beginning of a new line of research, within the protocol of therapeutic options, in the antenatal correction of congenital spina bifida.

Palabras clave : Fetal microneurosurgery; Congenital spina bifida; Myelomeningocele; Myeloschisis; patch; Allograft; Aponeurosis.

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