Abstract

CASTEJON S, Olivar C; MOLINARO V, María P; RIVAS, Alba E  and  SCUCCES M, María G. Vellosidades placentarias terminales filiformes en la anemia drepanocítica. Gac Méd Caracas [online]. 2003, vol.111, n.1, pp.17-22. ISSN 0367-4762.

To describe filiform placental villi, before described as terminal villi deficiency in the mature intermediate villi, found in ss hemoglobinopathy with light microscopy and scanning electron microscopy is our proposal in this work. Fifty hematoxilin eosine slides were observed in marginal, central or intermediate regions near to basal plate and specimens were taken to their observation with the scanning electron microscope. The findings indicate the presence of filiform villi in the conglomerate villi with elongated axis different to normal terminal villi. They show absent cytotrophoblast, variable trofoblast thickness and reduction of vasculosyncytial membranes. The distance from center of capillar lumen to the surface of trophoblast is large. This last feature and the stasis of erithrocytes into extremely elongated capillar damage the surface of interchange of gases and nutrients which predict intrauterine growth restriction.

Keywords : Filiform placental villi; Sickle cell disease.