Abstract

CASTEJON S, Olivar C et al. La placenta y el cordón umbilical del feto papiráceo en la anemia drepanocítica. Gac Méd Caracas [online]. 2003, vol.111, n.4, pp.280-286. ISSN 0367-4762.

To analyze the placenta and umbilical cord of a diamnionic-monochorionic pregnancy complicated with sickle cell anemia and fetal intrauterine death is the purpose of this study. Macroscopic and microscopic analysis of placental and umbilical regions were done of material obtained from a patient with sickle celi disease. Eccentric insertion, generalized cord edema and collapse appear to be the cause of death of the papyraceous fetus. Degenerative changes were observed in the umbilical cord and placental changes showed an increased fibrinoid deposition involving 40 % of the placental disk. Our findings have importance because morbidity and mortality of the surving fetus are high. Since fetofetal transfusion syndrome is observed in this placental type their possible occurrence in early pregnancy is discussed together to another factors of risk.

Keywords : Fetal death; Diamnionic-monochorionic pregnancy; Sickle cell disease.