Resumen

SALAZAR DE DUGARTE, Guillermina; FANEITE, Pedro; PINEDA, Francis  y  MOLINA, Francis. Valores normales de las alfa-fetoproteínas en embarazadas a las 24 y 28 semanas de gestación. Gac Méd Caracas [online]. 2007, vol.115, n.3, pp.213-218. ISSN 0367-4762.

Objective: To obtain the normal values of α-fetoprotein, between 24-28 weeks of pregnancy, to be use as levels of reference in the pregnancies with preterm delivery risk. Method: Longitudinal prospective study, non experimental, in 80 pregnant women attended between January to November 2005. Alfa-fetoprotein was determined by the Elisa technic. Results: The α-fetoprotein mean values oscilated between 112 ng/mL at 24 weeks and 133 ng/mL at 28 weeks, and in the percentile distribution with ranges of 60 ng/mL in the percentile 10 and 200 ng/mL in the percentile 90 at the 24 weeks. At 28 weeks the range were 82 ng/mL in the percentile 10 and 230 ng/mL in the 90 percentile. Conclusions: We have at one’s disposal α-fetoprotein values as a parameter to be used as pronostique in the high risk pregnancy of preterm delivery.

Palabras clave : -fetoprotein; -fetoprotein in pregnancy; -fetoprotein and preterm delivery; Prenatal diagnosis.