Abstract

HERNANDEZ, Alipio; CESPEDES, Ghislaine; LARA, Carmen  and  GONZALEZ, Jesús. Meningiomas: Hallazgos clínicos y morfológicos en una casuística de 24 años. Gac Méd Caracas. [online]. 2008, vol.116, n.2, pp.93-103. ISSN 0367-4762.

Meningiomas are frequent primary neoplasms of the central nervous system, usually benign and susceptible to healing through surgery. The clinical and morphological discoveries are presented in a study of 580 meningiomasdiagnosed during the period 1980-2003. These tumors represented a 16 % of the neoplasms of the central nervous system and most of them were unique (85 % of thecases), with preferential intracranial localization andclinical manifestations related to the size and localization of the tumor. Women were affected more frequently (the rate female/male of 2.4:1) and patients with ages among 30 and 59 years (67 % of the cases). According to the histologic classification of the World Health Organization, 80 % of the meningiomas corresponded to histological grade I (benign), 17 % to grade II (atypical) and only 3 % to grade III (malignant). The most frequent histological subtype was the transitional variant. It is important for the pathologist to recognize and classify adequately the meningiomas, since upon this depends the treatment and prognosis of this frequent kind of neoplasm.

Keywords : Meningioma; Histologic classification; Clinic.