Abstract

REYNA-VILLASMIL, Eduardo et al. Concentraciones de homocisteína y perfil lipídico en preeclámpticas. Gac Méd Caracas. [online]. 2008, vol.116, n.3, pp.235-240. ISSN 0367-4762.

The objective of the research was to compare plasma concentrations of homocysteine and lipid profile in preeclamptic and control patients and establish the relation between homocysteine and cholesterol, triglycerides and lipoprotein concentrations. Seventy patients w ere selected and divided in tw o groups, preeclamptic (group A) and norm otensive pregnant wom en (group B) considered as controls, studied in consecutive way. Concentrations of total cholesterol, triglycerides, high-density (HDL-C), low -density (LDL-C), very-low density lipoproteins (VLDL) and homocysteine were measured. There were significant statically differences in triglycerides, HDL-C, VLDL and homocysteine (P < 0.05). There w ere no significant differences in cholesterol and LDL-C concentrations. When preeclamptic group was analyzed exclusively, there were observed only significant and positive correlation between homocysteine and triglycerides (r = 0.229; P < 0.05). It is concluded that there are significant differences in triglycerides, HDL-C, VLDL and homocysteine between preeclamptic and normotensive controls. More over, there is a positive a significant correlation betw een hom ocysteine and triglycerides in preeclamptic patients.

Keywords : Preeclampsia; Homocysteine; Lipids; Lipoproteins.