Abstract

SALINAS, Nancy et al. Effect of partially refined palm oil in lipid profile in rats.. Invest. clín [online]. 2008, vol.49, n.1, pp.5-16. ISSN 0535-5133.

Palm oil is rich in carotenoids, tocopherols and tocotrienols. This oil is refined for its human consumption bringing as a consequence an alteration of their properties. The objective of this study was to evaluate the effect of the partially refined, bleached and deodorized palm oil (RBD red) on the lipid profile and levels of vitamin A (retinol) and E (a tocopherol) in 4 groups of rats: B (commercial food Protinal® for laboratory animals: ST + 5% egg yolk powder); C (ST + 5% egg yolk powder + 14 RBD red) both groups with induced hyperlipidemia; and D (ST + 14% RBD red), as compared with a control A (ST) during 35 days. The results were: the RBD red induced significative decreases of TC (total cholesterol) in groups C and D (81 ±11 mg/dL and 77 + 7 mg/dL), respectively, when compared with the control group (99 ± 11 mg/dL) for 35 days experimentation. Additionally, an increment of the HDL-C (53 ± 4 mg/dL) in the C group and in the D group (53 ± 5 mg/dL) were observed when compared with group B (44 ± 3 mg/dL), resulting in a lower ratio of TC/HDL-C (1.5 ± 0.1). In the groups C and D, there were significant increases (p < 0.05) in the serum concentrations of retinol (26 ± 5 µg/dL and 58 ± 18 µg/dL) and a tocopherol (165 ± 58 µg/dL) and 445 ± 65 µg/dL). These results allow to conclude that the supplementation with RBD red diminishes the TC, improving the ratio TC/HDL-C. The presence of a monosaturated fatty acid (oleic acid) and the high concentrations of micronutrients (á tocopherol and retinol) in RBD red palm oil, influence favorably the lipid profile of rats with induced hyperlipidemia

Keywords : Palm oil; cholesterol; triglycerides; carotenes; tocopherols.