Abstract

MARTINEZ, Dianny et al. Enterobacter cloacae productor de KPC y VIM en un Hospital del Noreste de Venezuela. Invest. clín [online]. 2015, vol.56, n.2, pp.182-187. ISSN 0535-5133.

An 83-year-old male patient is admitted to the central hospital in Cumaná, Venezuela with severe urinary infection, history of hospitalizations and prolonged antimicrobial treatments. A strain of Enterobacter cloacae was isolated showing resistance to multiple types of antibiotics (only sensitive to gentamicin), with phenotype of serine- and metallo-carbapenemases. Both, bla_VIM-2 and bla_KPC genes were detected in the isolate. This is the first report of an Enterobacteriaceae species producing both KPC carbapenemase and VIM metallo carbapenemase in Venezuela. This finding has a great clinical and epidemiological impact in the region, because of the feasibility of transferring these genes, through mobile elements to other strains of Enterobacter and to other infection-causing species of bacteria.

Keywords : Enterobacter; resistance; KPC; VIM; carbapenemases.