Abstract

NUNEZ-TROCONIS, José. Trichomonas vaginalis: pathogenesis and its role in cervical cancer. Invest. clín [online]. 2020, vol.61, n.4, pp.349-375.  Epub Feb 22, 2021. ISSN 0535-5133.  https://doi.org/10.22209/ic.v61n4a05.

The objective of this article was to review and to analyze the possible role that Trichomonas vaginalis has as a co-factor in the origin and development of cervical cancer. For that purpose, the Latin-American and international bibliography was reviewed using the Pub-Med, Google Scholar, Springer, the Cochrane Library, Embase, Scielo, Imbiomed-L, Redalyc and Latindex web sites. The searches included the key words: Trichomonas vaginalis, epidemiology of Trichomonas vaginalis, epidemiology of cervical cancer, inflam mation mechanisms, Trichomonas vaginalis and inflammation mechanisms, Trichomonas viruses, carcinogenesis, cervical cancer and co-factors, sexually transmitted infections and cervical cancer, cancer and inflammation mechanisms, Trichomonas vaginalis and cervical cancer. Publications from 1970 to June 2020 were reviewed and analyzed. This review article analyzes the possible mechanisms that Trichomonas vaginalis could play in the carcinogenesis of the cervical cancer as a co-factor with the human papilloma virus or as an independent factor.

Keywords : Trichomonas vaginalis; cancer of the cervix; inflammation mechanisms; carcinogenesis; sexual transmitted infection; Trichomonas vaginalis virus.

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