Abstract

QIU, Zhichao; CAI, Jingjing  and  XIA, Fanlin. Correlation between the degree of cognitive impairment and emotional state in patients with Alzheimer’s disease. Invest. clín [online]. 2024, vol.65, n.1, pp.37-47.  Epub Mar 09, 2024. ISSN 0535-5133.  https://doi.org/10.54817/ic.v65n1a04.

This study aimed to investigate the correlation between cognitive dysfunction and emotional state in patients with Alzheimer’s disease and then propose intervention strategies. One hundred twenty-five patients with Alzheimer’s disease from June 2019 to May 2022 were selected as the study subjects and divided into two groups based on the degree of cognitive impairment, both receiving routine drug treatment and cognitive rehabilitation intervention. The Montreal Cognitive Assessment (MoCA) and the Positive and Negative Affect Scale (PANAS) were used to evaluate the cognitive function and emotional status of two groups of patients before the intervention and four and eight weeks of intervention and to analyze the correlations between the two. The results showed statistically significant differences between the two groups MoCA and PANAS scores (P<0.05). Before the intervention, the patient’s MoCA score was positively correlated with the PANAS positive emotion score and negatively correlated with the PANAS negative emotion score (P<0.05). After four and eight weeks of intervention, the patient’s MoCA score was positively correlated with the PANAS positive emotion score (P<0.05) and negatively correlated with the PANAS negative emotion score (P<0.05).

Keywords : Alzheimer’s disease; cognitive dysfunction; positive emotion; negative emotion.

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