Abstract

SOUCRE, Natalia; BRACHO, Verónica; ALVARADO, Primavera  and  CAVALLERA, Elsy. The efficacy of ozonated oils in the treatment of patients with superficial mycosis. Invest. clín [online]. 2024, vol.65, n.3, pp.294-307.  Epub Sep 12, 2024. ISSN 0535-5133.  https://doi.org/10.54817/ic.v65n3a03.

Superficial mycoses are one of the main reasons for consultation in the dermatological area. In recent years, the therapeutic effectiveness of ozonated oils in fungal infections has been verified in different countries due to its broad germicidal and antifungal spectrum. The objective is to evaluate the efficacy of the use of ozonated sunflower oil in the treatment of superficial mycoses in patients of the Mycology consultation at the Dermatology Service of the Hospital Vargas de Caracas, Instituto Autonómo de Biomedicina “Dr. Jacinto Convit”. A cross-sectional descriptive, experimental study was conducted, where 36 patients diagnosed with superficial mycosis and ten healthy subjects were evaluated. Of the group of 36 patients, 26 were treated with ozonated sunflower oil (AGO) and ten patients with non-ozonized sunflower oil (AGNO). Ten healthy individuals represented the AGO sensitivity control. The most frequent superficial mycosis evaluated in the AGO group was tinea corporis (31%), followed by denture stomatitis (23%) and for the AGNO group, tinea pedis (50%). Regarding the etiological agent, an improvement with the AGO treatment of 86% for Candida albicans and 60% for the Trichophyton rubrum complex was evidenced at week eight of treatment. It is concluded that the antifungal effect of AGO is more significant for the genus Candida spp than for dermatophytes, evidencing a total improvement of the lesions with six weeks of treatment.

Keywords : superficial mycoses; ozonated oils; antifungal; ozone.

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